B7-H4 is a positive regulator of antitumor immunity.
نویسندگان
چکیده
B7-H4 (B7x, B7S1, VTCN1, DD-0110) is a member of the B7 superfamily that negatively regulates T cell responses.1 In addition, B7-H4 expression is increased on tumors and has been shown to be a negative prognostic marker for many cancers.2 Unexpectedly our recent study demonstrated that B7-H4 inhibited tumor growth and was required to promote effective antitumor responses.3.
منابع مشابه
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ورودعنوان ژورنال:
- Oncoimmunology
دوره 5 1 شماره
صفحات -
تاریخ انتشار 2016